内容简介：

Computational Non-coding RNA Biology is a resource for the computation of non-coding RNAs. The book covers computational methods for the identification and quantification of non-coding RNAs, including miRNAs, tasiRNAs, phasiRNAs, lariat originated circRNAs and back-spliced circRNAs, the identification of miRNA/siRNA targets, and the identification of mutations and editing sites in miRNAs. The book introduces basic ideas of computational methods, along with their detailed computational steps, a critical component in the development of high throughput sequencing technologies for identifying different classes of non-coding RNAs and predicting the possible functions of these molecules.

Finding, quantifying, and visualizing non-coding RNAs from high throughput sequencing datasets at high volume is complex. Therefore, it is usually possible for biologists to complete all of the necessary steps for analysis.

计算非编码 RNA 生物学是计算非编码 RNA 的资源。本书涵盖了非编码 RNA 的鉴定和定量计算方法，包括 miRNA、tasiRNA、phasiRNA、lariat 起源的 circRNA 和反剪接 circRNA、miRNA/siRNA 靶标的鉴定以及 miRNA 中突变和编辑位点的鉴定。本书介绍了计算方法的基本思想及其详细的计算步骤，这是开发高通量测序技术的关键组成部分，用于识别不同类别的非编码 RNA 并预测这些分子的可能功能。从高通量测序数据集中查找、定量和可视化非编码 RNA 非常复杂。因此，生物学家通常可以完成所有必要的分析步骤。