陈丽 有机化学专业博士              

讲师 硕士生导师

一、工作学习经历

2014-09 至 2018-06，云南大学, 制药工程, 学士

2018-09 至 2024-06，云南大学, 有机化学 博士

2024-09 至今，昆明理工大学生命科学与技术学院，硕士生导师

二、研究领域

利用有机化学、药物化学知识去研究类天然杂环药物分子的设计与合成，发展环境友好的绿色溶剂、多组分一锅法、不对称合成及光催化氧化还原等多种合成方法，从而产生新颖的合成设计策略，以简便、快捷、高效的方法快速地构建结构新颖的类天然药物分子库，并对化合物库进行相关的生物活性研究。

三、开设的课程

《现代合成方法与技术》、《高等有机化学》、《基础有机化学》、《制药分离工程》

四、代表性论文 （近五年）

[1] Li Chen, Rong Huang, Kun Li, Xing-Han Yun, Chang-Long Yang and Sheng-Jiao Yan*, An environmentally benign cascade reaction of chromone-3-carboxaldehydes with ethyl 2-(pyridine-2-yl)acetate derivatives for highly site-selective synthesis of quinolizines and quinolizinium salts in water, Green Chemistry, 2020, 22, 6943–6953.

[2] Li Chen, Rong Huang, Xing-Han Yun, Tian-Hui Hao and Sheng-Jiao Yan*, Multi-component cascade reaction of 3-formylchromones: highly selective synthesis of 4,5-dihydro-[4,5'-bipyrimidin]-6(1H)-one derivatives, Chemical Communications, 2021, 57, 7657–7660.

[3] Li Chen, Yuan-Da Li, Ying Lv, Zi-Han Lu and Sheng-Jiao Yan*, Cu-Catalyzed decarboxylative annulation of N-substituted glycines with 3-formylchromones: synthesis of functionalized chromeno[2,3-b]pyrrol-4(1H)-ones, Chemical Communications, 2022, 58, 10194–10197.

[4] Li Chen, Jin-Mei Qi, Shu Yang, Si-Nuo Sun and Sheng-Jiao Yan*, Cu-catalyzed decarboxylative annulation of proline derivatives: multi-component synthesis of functionalized chromeno[2,3-c]-pyrrol-9(1H)-one derivatives, Organic Chemistry Frontiers, 2023, 10, 2994–2999.

[5] Wei Yuanzheng, Chen Longkun, Hu Huimin, Zhang Yu, Yang Shaolin, Xu Yu, Chen Li*, Yu Fuchao*. Catalyst-free sequential Wolff rearrangement and [3+3] annulation of enaminones and diazo compounds enabling the assembly of highly functionalized pyridin-4-ones. Adv. Synth. Catal. 2025, 367, e202401561.

[6] Wang Xiaohong, Peng Menglin, Wang Yijin, Song Siyu, Xu Ying, Chen Li*, Yu Fuchao*. Difunctionalization/Chromone Annulation Reaction of o-Hydroxyaryl Enaminones, Water, and Aryldiazonium Salts. Molecules 2025, 30, 1194.

[7] Hu Huimin, Wei Yuanzheng, Xu Ying, Peng Menglin, Yang Shaolin, Xu Yu, Zhang Yu, Chen Li*, Yu Fuchao*, Switchable Divergent Synthesis of 3-Dithiocarbamyl and 3-Carbamothioyl Chromones Through Chromone Annulation Reactions of o-Hydroxyenaminones With CS2, Adv. Synth. Catal., 2025, 368, e70260.

[8] Xu Yu, Zhang Zhilai, Yang Shaolin, Zhang Yu, Peng Menglin, Hu Huimin, Wei Yuanzheng, Chen Li*, Yu Fuchao*, Rh(III)-Catalyzed [3+3] Annulation of Cyclopropenones with Iodonium Ylides for the Synthesis of 2,5-Dihydrochromenediones, J. Org. Chem. 2026, 91, 2506.

[9] Chen Li, Luo Qin, Jian Cen, Yan Sheng-Jiao*, Photocatalyzed Decarboxylative Annulation of N-Arylglycines with Cyclopropenones: Synthesis of Highly Functionalized Pyrrol-2-Ones, J. Org. Chem. 2026, 91, 8598.

[10] Xu Ying, Peng Menglin, Wei Yuanzheng, Xu Yu, Yang Shaolin, Wang Xiaohong, Chen Li*, Yu Fuchao*, Rh(III)-Catalyzed Selective Mono- and Dual C-H Bond Functionalization of N-Aryl Benzamidines with Iodonium Ylides, 2026, DOI: 10.1039/D6CC03493D.

五、主持项目（近五年）

2022年云南省教育厅科学研究基金项目，已结题

六、荣誉、奖励及参加学术团体的情况（近五年）

2020年硕士研究生国家奖学金

2022年博士研究生国家奖学金

七、联系方式

地址：云南省昆明市呈贡区景明南路727号生命科学与技术学院药物合成课题组B419

E-mail：chenli@kust.edu.cn