陈宣钦-昆明理工大学生命科学与技术学院

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陈宣钦

作者：时间：2023-03-08

说明: 小1寸

陈宣钦博士

教授，硕士生导师

一、工作学习经历

1999-2003 江西农业大学，农学学士

2003-2006 南京农业大学，植物学硕士

2006-2010 中国科学院大学，植物学博士

2010-至今昆明理工大学生命科学与技术学院，讲师/副教授/教授,硕士生导师

二、研究领域

天然产物的结构和功能：利用现代分离和波普技术，高效和快速的鉴定传统中药中的各种化学成分。采用体外和体内活性筛选模型，探讨天然小分子化合物的活性及其可能的作用机理，解析传统中药治疗疾病的物质基础。

三、开设的课程

《天然药物化学》，《药物化学》和《高级天然药物化学》

四、代表性论文

1. Chen XQ, Gao LH, Li YP, Li HM, Liu D, Liao XL, Li RT^#. 2017. Highly oxygenated grayanane diterpenoids from flowers of Pieris japonica and structure-activity relationships of antifeedant activity against Pieris brassicae.Journal of Agricultural and Food Chemistry, 65: 4456.

2. Zhou XQ, Li SQ,Liao CC,Dai WF,Rao KR,Ma XR,Li RT^#,Chen, XQ^#. 2021.Structurally diversified ent-kaurane and abietane diterpenoids from the stems of Tripterygium wilfordii and their anti-inflammatory activity.Bioorganic Chemistry, 115, 105178.

3. Wang SY, Li JC, Li D,Yang T,Chen XQ^#, Li RT^#. 2021.Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity. Phytochemistry,188, 112775.

4. Yant T, Wang SY, Li HM, Zhao Q, Yan SL, Dong M, Liu D^#,Chen XQ^#, Li RT^#. 2020. Lathyrane diterpenes fromEuphorbia lathyris and the potential mechanism to reverse the multi-drug resistance in HepG2/Adr cells. Biomedicine Pharmacotherapy, 121,109663.

5. Yang T, Wang SY, Zheng H, Wang L, Liu D,Chen XQ^#, Li RT^#. 2019. Understanding dihydro-β-agarofuran sesquiterpenes fromTripterygium hypoglaucumas the modulators of multi-drug resistance in HepG2/Adr cells. Biochemical and Biophysical Research Communications, 508:742.

五、主持项目

国家自然科学基金3项（2项结题），云南省自然科学基金2项，国家重点实验室开放基金2项

六、联系方式

邮箱：chenxuanqin12@sina.com

地址：昆明市呈贡区昆明理工大学生命科学与技术学院

陈宣钦

3. Wang SY, Li JC, Li D,Yang T,Chen XQ#, Li RT#. 2021.Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity. Phytochemistry,188, 112775.

4. Yant T, Wang SY, Li HM, Zhao Q, Yan SL, Dong M, Liu D#,Chen XQ#, Li RT#. 2020. Lathyrane diterpenes fromEuphorbia lathyris and the potential mechanism to reverse the multi-drug resistance in HepG2/Adr cells. Biomedicine Pharmacotherapy, 121,109663.

5. Yang T, Wang SY, Zheng H, Wang L, Liu D,Chen XQ#, Li RT#. 2019. Understanding dihydro-β-agarofuran sesquiterpenes fromTripterygium hypoglaucumas the modulators of multi-drug resistance in HepG2/Adr cells. Biochemical and Biophysical Research Communications, 508:742.

3. Wang SY, Li JC, Li D,Yang T,Chen XQ^#, Li RT^#. 2021.Ingenane and jatrophane-type diterpenoids from Euphorbia kansui with multidrug resistance reversal activity. Phytochemistry,188, 112775.

4. Yant T, Wang SY, Li HM, Zhao Q, Yan SL, Dong M, Liu D^#,Chen XQ^#, Li RT^#. 2020. Lathyrane diterpenes fromEuphorbia lathyris and the potential mechanism to reverse the multi-drug resistance in HepG2/Adr cells. Biomedicine Pharmacotherapy, 121,109663.

5. Yang T, Wang SY, Zheng H, Wang L, Liu D,Chen XQ^#, Li RT^#. 2019. Understanding dihydro-β-agarofuran sesquiterpenes fromTripterygium hypoglaucumas the modulators of multi-drug resistance in HepG2/Adr cells. Biochemical and Biophysical Research Communications, 508:742.